Monday, February 22, 2021

Yale scientists repair injured spinal cord using patients' own stem cells


https://www.eurekalert.org/pub_releases/2021-02/yu-ysr022221.php

 

News Release 22-Feb-2021
Yale University

 

Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery.

For more than half of the patients, substantial improvements in key functions -- such as ability to walk, or to use their hands -- were observed within weeks of stem cell injection, the researchers report. No substantial side effects were reported.


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"Similar results with stem cells in patients with stroke increases our confidence that this approach may be clinically useful," noted Kocsis. "This clinical study is the culmination of extensive preclinical laboratory work using MSCs between Yale and Sapporo colleagues over many years."

"The idea that we may be able to restore function after injury to the brain and spinal cord using the patient's own stem cells has intrigued us for years," Waxman said. "Now we have a hint, in humans, that it may be possible." 


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