Men who are unemployed for more than two years show signs of faster ageing in their DNA, a new study has found.

http://www.eurekalert.org/pub_releases/2013-11/icl-lum111813.php

PUBLIC RELEASE DATE:
20-Nov-2013
Contact: Sam Wong
Imperial College London

Long-term unemployment may accelerate aging in men

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They measured structures called telomeres, which lie at the ends of chromosomes and protect the genetic code from being degraded. Telomeres become shorter over a person's lifetime, and their length is considered a marker for biological ageing. Short telomeres are linked to higher risk of age-related diseases such as type 2 diabetes and heart disease.

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The researchers looked at telomere length in blood cells from samples collected in 1997, when the participants were all 31 years old. The study, funded by the Wellcome Trust, found that men who had been unemployed for more than two of the preceding three years were more than twice as likely to have short telomeres compared to men who were continuously employed,.

The analysis accounted for other social, biological and behavioural factors that could have affected the result, helping to rule out the possibility that short telomeres were linked to medical conditions that prevented participants from working.

This trend was not seen in women, which may be because fewer women than men in the study were unemployed for long periods in their 30s. Whether long-term unemployment is more harmful for men than women later in life needs to be addressed in future studies.

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