Tuesday, September 22, 2020

Lower zinc levels in the blood are associated with an increased risk of death in patients with COVID-19


News Release 22-Sep-2020
European Society of Clinical Microbiology and Infectious Diseases

New research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, held online from 23-25 September) shows that having a lower level of zinc in the blood is associated with a poorer outcome in patients with COVID-19. The study is by Dr Roberto Güerri-Fernández, Hospital Del Mar, Barcelona, Spain, and colleagues.

Increased intracellular zinc concentrations efficiently impair replication/reproduction of a number of viruses.


After adjusting by age, sex, severity and receiving hydroxychloroquine, statistical analysis showed each unit increase of plasma zinc at admission to hospital was associated with a 7% reduced risk of in-hospital mortality. Having a plasma zinc level lower than 50mcg/dl at admission was associated with a 2.3 times increased risk of in-hospital death compared with those patients with a plasma zinc level of 50mcg/dl or higher.



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