Sunday, October 20, 2013

Disrupted sleep may make heavy drinkers particularly prone to liver disease


Disrupted sleep and circadian rhythm — the body's internal clock — may play a role in the development of liver disease for those who are vulnerable due to heavy drinking, according to research conducted at Rush University Medical Center. For purposes of the study, was defined as receiving 29 percent of all daily calories from alcohol.

The study, which was published in the August issue of the journal PLOS ONE, showed that disruption of circadian rhythms, which is often seen in shift workers and those suffering from jet lag, weakened the lining of the gut (a condition known as leaky gut) in a clinical lab setting. People with leaky gut are vulnerable to illnesses such as liver disease because the weakening of the intestinal wall allows toxins to enter the bloodstream.


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