Thursday, May 31, 2012

Facts in Scientific Drug Literature May Not Be

http://www.sciencedaily.com/releases/2012/05/120529181145.htm

ScienceDaily (May 29, 2012) — A growing concern with fraud and misconduct in published drug studies has led researchers at the University of Illinois at Chicago's Center for Pharmacoeconomic Research to investigate the extent and reasons for retractions in the research.

"We were surprised to find the proportion of retractions due to scientific misconduct in the drug literature is higher than in general biomedical literature," said Simon Pickard, associate professor of pharmacy practice and senior author of a study published in the journal Pharmacotherapy.

Nearly three-quarters of the retracted drug studies were attributed to scientific misconduct, he said, "which includes data falsification or fabrication, questionable veracity, unethical author conduct, or plagiarism. While these studies comprise a small percentage of the overall literature, health care professionals may rely on this evidence to make treatment recommendations."

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The UIC team found that a considerable number of the retracted papers were attributable to two authors, one based in Japan and the other in Germany.

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