Historical analysis examines sugar industry role in heart disease research

https://www.eurekalert.org/pub_releases/2016-09/tjnj-hae090816.php

Public Release: 12-Sep-2016
Historical analysis examines sugar industry role in heart disease research
The JAMA Network Journals

Using archival documents, a new report published online by JAMA Internal Medicine examines the sugar industry's role in coronary heart disease research and suggests the industry sponsored research to influence the scientific debate to cast doubt on the hazards of sugar and to promote dietary fat as the culprit in heart disease.

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"This historical account of industry efforts demonstrates the importance of having reviews written by people without conflicts of interest and the need for financial disclosure," note the authors, who point out the NEJM has required authors to disclose all conflicts of interest since 1984. There also is no direct evidence that the sugar industry wrote or changed the NEJM review manuscript and evidence that that the industry shaped its conclusions is circumstantial, the authors acknowledge.

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"This study suggests that the sugar industry sponsored its first CHD [coronary heart disease] research project in 1965 to downplay early warning signs that sucrose consumption was a risk factor in CHD. As of 2016, sugar control policies are being promulgated in international, federal, state and local venues. Yet CHD risk is inconsistently cited as a health consequence of added sugars consumption. Because CHD is the leading cause of death globally, the health community should ensure that CHD risk is evaluated in future risk assessments of added sugars. Policymaking committees should consider giving less weight to food industry-funded studies, and include mechanistic and animal studies as well as studies appraising the effect of added sugars on multiple CHD biomarkers and disease development," the article concludes.

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