High-Fat Diet During Pregnancy Programs Child for Future Diabetes, Study Suggests

http://www.sciencedaily.com/releases/2011/05/110525164110.htm

ScienceDaily (May 25, 2011) — A high-fat diet during pregnancy may program a woman's baby for future diabetes, even if she herself is not obese or diabetic, says a new University of Illinois study published in the Journal of Physiology.

"We found that exposure to a high-fat diet before birth modifies gene expression in the livers of offspring so they are more likely to overproduce glucose, which can cause early insulin resistance and diabetes," said Yuan-Xiang Pan, a U of I professor of nutrition.

The high-fat diet that caused these changes was a typical Western diet that contained 45 percent fat, which is not at all unusual, he said
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