The coronavirus is killing about 1 in 10 hospitalized middle-aged patients and 4 in 10 older than 85 in the United States, and is particularly lethal to men even when taking into account common chronic diseases that exacerbate risk

https://www.washingtonpost.com/national/health-science/medical-databases-show-1-in-10-hospitalized-middle-aged-coronavirus-patients-in-us-do-not-survive/2020/04/11/284485a2-7bfe-11ea-b6ff-597f170df8f8_story.html

By Joel Achenbach
April 11, 2020 at 9:00 p.m. EDT

The coronavirus is killing about 1 in 10 hospitalized middle-aged patients and 4 in 10 older than 85 in the United States, and is particularly lethal to men even when taking into account common chronic diseases that exacerbate risk, according to previously unpublished data from a company that aggregates real-time patient data from 1,000 hospitals and 180,000 health-care providers.

Allscripts, through its subsidiary CarePort Health, released the data collected from multiple electronic health record companies across the nation. It does not identify patients by name.

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The new data do not cover everyone infected by the virus, only patients who have been hospitalized. The CarePort data come from facilities in 43 states. The high death rates in the data reflect the fact that hospitals typically admit only patients with severe symptoms, CarePort CEO Lissy Hu said.

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This broader swath of data largely echoes the CDC findings. One difference: CarePort found that, after adjusting the estimated mortality rate to take age into account, chronic kidney disease appears to correspond to a 2.5 times greater risk of death among hospitalized patients.

According to CarePort, an 85-year-old who has no chronic diseases and is hospitalized faces a mortality risk between 22 and 27 percent. But if the person has what is known as existing acute kidney injury, the mortality rate spikes to 39 to 49 percent.

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Among the common diseases associated with higher levels of mortality from covid-19 are diabetes, lung disease and heart disease.

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The new data show that, even when controlling for age and the most common chronic diseases, men are 1.3 times as likely as women to die in the hospital from covid-19. This is consistent with observations in China and Italy, and it remains unexplained.

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being male, she said, “seems to increase risk even when you take into account very common underlying conditions.”

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This is preliminary data, and Allscripts cautions that the numbers could change as more patient records are compiled.

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