Stress exposure during pregnancy observed in mothers of children with autism

http://www.eurekalert.org/pub_releases/2016-06/uom-sed060716.php

Public Release: 7-Jun-2016
Stress exposure during pregnancy observed in mothers of children with autism
More research needed to understand gene-stress interaction
University of Missouri-Columbia

Stress during pregnancy has been linked to several conditions, including some instances of autism spectrum disorder. Now, researchers at the University of Missouri School of Medicine have observed a variant of a stress-sensitive gene and exposure to stress during pregnancy among two groups of mothers of children with autism. The researchers believe the finding could be a step toward helping identify women who have greater risks for having children with autism when exposed to stressors during a specific time window during pregnancy.

"Autism was thought to be largely a genetic disorder, but previous research has shown that environmental influences such as stress can play an important role in the development of the condition," said David Beversdorf, M.D., associate professor in the departments of radiology, neurology and psychological sciences at the University of Missouri and the MU Thompson Center for Autism and Neurodevelopmental Disorders, and senior author of the study. "We know that some mothers who experience significant levels of stress don't have children with autism, but others do. To help understand why, we studied a gene that is known to affect stress and found a link between it and the development of autism with exposure to stress."

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