High Selenium and vitamin E supplementation may raise prostate cancer risk

Moderation is best in both things. Both selenium and vitamin E are important for health, but like many things, harmful in excess.

http://www.eurekalert.org/pub_releases/2014-02/oup-sv021914.php

PUBLIC RELEASE DATE: 21-Feb-2014
Contact: Zachary Rathner
Oxford University Press
Selenium and vitamin E supplementation over recommended dietary intake may raise PC risk

In a large clinical trial testing dietary supplements for prostate cancer (PCa) prevention, baseline selenium (Se) status (measured by toenail Se concentration), in the absence of supplementation, was not associated with prostate cancer (PCa) risk. However, when baseline toenail Se concentrations were high, supplementation with high-dose Se almost doubled the risk of high-grade PCa risk among older men, according to a new study published February 21 in the Journal of the National Cancer Institute.

High-dose vitamin E also more than doubled the risk high-grade PCa risk, but only among men with low baseline toenail Se concentrations.