Saturday, February 22, 2014

Chemical Study Becomes A Tale of Conspiracy

Syngenta executives are worth every penny of their high income, because they work so hard to make money, and to cover up dangerous effects of their products. [sarcasm]

I strongly suggest reading the whole article, as well as the following interview with Professor Hayes, which I reference below in this blog post.

http://www.democracynow.org/2014/2/21/silencing_the_scientist_tyrone_hayes_on

Besides the issue of companies covering up danger from their products, and influencing government regulation, there is the fact that because of decreased government funding of universities, the universities are becoming dependent on these companies, and the results of research influenced by this.

Note that around the world, male sperm counts have been falling.

I am happy that NPR did an interview about the New Yorker article. I have included info from the interview below. But I also cannot help noticing that NPR only reported on it after it was in the New Yorker. So the info was bound to end up on the blogosphere. Now NPR can get credit with liberals for airing this, w/o doing any additional harm to this company, even if it turns out that it is a corporate donor of NPR.

http://www.newyorker.com/reporting/2014/02/10/140210fa_fact_aviv?currentPage=all

by Rachel Aviv
February 10, 2014

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In 2001, seven years after joining the biology faculty of the University of California, Berkeley, Tyrone Hayes stopped talking about his research with people he didn’t trust. He instructed the students in his lab, where he was raising three thousand frogs, to hang up the phone if they heard a click, a signal that a third party might be on the line. Other scientists seemed to remember events differently, he noticed, so he started carrying an audio recorder to meetings.

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Three years earlier, Syngenta, one of the largest agribusinesses in the world, had asked Hayes to conduct experiments on the herbicide atrazine, which is applied to more than half the corn in the United States. Hayes was thirty-one, and he had already published twenty papers on the endocrinology of amphibians. David Wake, a professor in Hayes’s department, said that Hayes “may have had the greatest potential of anyone in the field.” But, when Hayes discovered that atrazine might impede the sexual development of frogs, his dealings with Syngenta became strained, and, in November, 2000, he ended his relationship with the company.

Hayes continued studying atrazine on his own, and soon he became convinced that Syngenta representatives were following him to conferences around the world. He worried that the company was orchestrating a campaign to destroy his reputation. He complained that whenever he gave public talks there was a stranger in the back of the room, taking notes. On a trip to Washington, D.C., in 2003, he stayed at a different hotel each night. He was still in touch with a few Syngenta scientists and, after noticing that they knew many details about his work and his schedule, he suspected that they were reading his e-mails. To confuse them, he asked a student to write misleading e-mails from his office computer while he was travelling. He sent backup copies of his data and notes to his parents in sealed boxes. In an e-mail to one Syngenta scientist, he wrote that he had “risked my reputation, my name . . . some say even my life, for what I thought (and now know) is right.”

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They moved to Berkeley, where Hayes enrolled in the university’s program in integrative biology. He completed his Ph.D. in three and a half years, and was immediately hired by his department. “He was a force of nature—incredibly gifted and hardworking,” Paul Barber, a colleague who is now a professor at U.C.L.A., says.

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Liu and several other former students said that they had remained skeptical of Hayes’s accusations until last summer, when an article appeared in Environmental Health News (in partnership with 100Reporters)* that drew on Syngenta’s internal records. Hundreds of Syngenta’s memos, notes, and e-mails have been unsealed following the settlement, in 2012, of two class-action suits brought by twenty-three Midwestern cities and towns that accused Syngenta of “concealing atrazine’s true dangerous nature” and contaminating their drinking water. Stephen Tillery, the lawyer who argued the cases, said, “Tyrone’s work gave us the scientific basis for the lawsuit.”

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Hayes has devoted the past fifteen years to studying atrazine, and during that time scientists around the world have expanded on his findings, suggesting that the herbicide is associated with birth defects in humans as well as in animals. The company documents show that, while Hayes was studying atrazine, Syngenta was studying him, as he had long suspected. Syngenta’s public-relations team had drafted a list of four goals. The first was “discredit Hayes.” In a spiral-bound notebook, Syngenta’s communications manager, Sherry Ford, who referred to Hayes by his initials, wrote that the company could “prevent citing of TH data by revealing him as noncredible.” He was a frequent topic of conversation at company meetings. Syngenta looked for ways to “exploit Hayes’ faults/problems.”




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Hayes repeated the experiments using funds from Berkeley and the National Science Foundation. Afterward, he wrote to the panel, “Although I do not want to make a big deal out of it until I have all of the data analyzed and decoded—I feel I should warn you that I think something very strange is coming up in these animals.” After dissecting the frogs, he noticed that some could not be clearly identified as male or female: they had both testes and ovaries. Others had multiple testes that were deformed.

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In January, 2001, Syngenta employees and members of the EcoRisk panel travelled to Berkeley to discuss Hayes’s new findings. Syngenta asked to meet with him privately, but Hayes insisted on the presence of his students, a few colleagues, and his wife.

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After lunch, Syngenta introduced a guest speaker, a statistical consultant, who listed numerous errors in Hayes’s report and concluded that the results were not statistically significant. Hayes’s wife, Katherine Kim, said that the consultant seemed to be trying to “make Tyrone look as foolish as possible.” Wake, the biology professor, said that the men on the EcoRisk panel looked increasingly uncomfortable. “They were experienced enough to know that the issues the statistical consultant was raising were routine and ridiculous,” he said. “A couple of glitches were presented as if they were the end of the world. I’ve been a scientist in academic settings for forty years, and I’ve never experienced anything like that. They were after Tyrone.”

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When he explained what had happened to Theo Colborn, the scientist who had popularized the theory that industrial chemicals could alter hormones, she advised him, “Don’t go home the same way twice.” Colborn was convinced that her office had been bugged, and that industry representatives followed her. She told Hayes to “keep looking over your shoulder” and to be careful whom he let in his lab. She warned him, “You have got to protect yourself.”

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The P.R. team suggested that the company “purchase ‘Tyrone Hayes’ as a search word on the internet, so that any time someone searches for Tyrone’s material, the first thing they see is our material.” The proposal was later expanded to include the phrases “amphibian hayes,” “atrazine frogs,” and “frog feminization.” (Searching online for “Tyrone Hayes” now brings up an advertisement that says, “Tyrone Hayes Not Credible.”)

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Fussy critiques of scientific experiments have become integral to what is known as the “sound science” campaign, an effort by interest groups and industries to slow the pace of regulation. David Michaels, the Assistant Secretary of Labor for Occupational Safety and Health, wrote, in his book “Doubt Is Their Product” (2008), that corporations have developed sophisticated strategies for “manufacturing and magnifying uncertainty.” In the eighties and nineties, the tobacco industry fended off regulations by drawing attention to questions about the science of secondhand smoke. Many companies have adopted this tactic. “Industry has learned that debating the science is much easier and more effective than debating the policy,” Michaels wrote. “In field after field, year after year, conclusions that might support regulation are always disputed. Animal data are deemed not relevant, human data not representative, and exposure data not reliable.”

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Nonetheless, Steeger [a scientist from the EPA] seemed resigned to the frustrations of regulatory science and gently punctured Hayes’s idealism. When Hayes complained that Syngenta had not reported his findings on frog hermaphroditism quickly enough, he responded that it was “unfortunate but not uncommon for registrants to ‘sit’ on data that may be considered adverse to the public’s perception of their products.” He wrote that “science can be manipulated to serve certain agendas. All you can do is practice ‘suspended disbelief.’ ”

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In 2003, a Syngenta development committee in Basel approved a strategy to keep atrazine on the market “until at least 2010.” A PowerPoint presentation assembled by Syngenta’s global product manager explained that “we need atrazine to secure our position in the corn marketplace. Without atrazine we cannot defend and grow our business in the USA.” Sherry Ford, the communications manager, wrote in her notebook that the company “should not phase out atz until we know about” the Syngenta herbicide paraquat, which has also been controversial, because of studies showing that it might be associated with Parkinson’s disease. She noted that atrazine “focuses attention away from other products.”

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Syngenta intensified its public-relations campaign in 2009, as it became concerned that activists, touting “new science,” had developed a “new line of attack.” That year, a paper in Acta Paediatrica, reviewing national records for thirty million births, found that children conceived between April and July, when the concentration of atrazine (mixed with other pesticides) in water is highest, were more likely to have genital birth defects. The author of the paper, Paul Winchester, a professor of pediatrics at the Indiana University School of Medicine, received a subpoena from Syngenta, which requested that he turn over every e-mail he had written about atrazine in the past decade.

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A few months after Winchester’s paper appeared, the Times published an investigation suggesting that atrazine levels frequently surpass the maximum threshold allowed in drinking water. The article referred to recent studies in Environmental Health Perspectives and the Journal of Pediatric Surgery that found that mothers living close to water sources containing atrazine were more likely to have babies who were underweight or had a defect in which the intestines and other organs protrude from the body.

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Michelle Boone, a professor of aquatic ecology at Miami University, who served on the E.P.A.’s scientific advisory panel, said, “We all follow the Tyrone Hayes drama, and some people will say, ‘He should just do the science.’ But the science doesn’t speak for itself. Industry has unlimited resources and bully power. Tyrone is the only one calling them out on what they’re doing.”

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After the hearing, two of the independent experts who had served on the E.P.A.’s scientific advisory panel, along with fifteen other scientists, wrote a paper (not yet published) complaining that the agency had repeatedly ignored the panel’s recommendations and that it placed “human health and the environment at the mercy of industry.” “The EPA works with industry to set up the methodology for such studies with the outcome often that industry is the only institution that can afford to conduct the research,” they wrote.

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In another paper, in Policy Perspective, Jason Rohr, an ecologist at the University of South Florida, who served on an E.P.A. panel, criticized the “lucrative ‘science for hire’ industry, where scientists are employed to dispute data.” He wrote that a Syngenta-funded review of the atrazine literature had arguably misrepresented more than fifty studies and made a hundred and forty-four inaccurate or misleading statements, of which “96.5% appeared to be beneficial for Syngenta.” Rohr, who has conducted several experiments involving atrazine, said that, at conferences, “I regularly get peppered with questions from Syngenta cronies trying to discount my research. They try to poke holes in the research rather than appreciate the adverse effects of the chemicals.” He said, “I have colleagues whom I’ve tried to recruit, and they’ve told me that they’re not willing to delve into this sort of research, because they don’t want the headache of having to defend their credibility.”

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[Following is from an interview on NPR with about the article above, with reporter Rachel Aviv]

http://www.npr.org/2014/02/05/272100022/chemical-study-becomes-a-tale-of-conspiracy-and-paranoia

Chemical Study Becomes A Tale of Conspiracy And Paranoia
February 05, 2014
ALL THINGS CONSIDERED from NPR News
MELISSA BLOCK, HOST
AUDIE CORNISH, HOST

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AVIV: I think at some point, there has to be an acknowledgement that the science is never going to be ideal. We can only get so far, particularly when we're looking at the effects of chemicals on humans - because we can never test them in the perfect way, which would be to feed the chemical to humans and see what happens. So there's always going to be this zone of uncertainty. And I think that the way that Europe has dealt with this is to acknowledge that when there's - when we reach a certain degree of uncertainty, maybe we should slow down whereas in the U.S., the general approach has been to keep going until we have absolute proof that a chemical has harms.

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The following is from an interview with Professor Hayes at the following link, which I strongly suggest reading in whole:

http://www.democracynow.org/2014/2/21/silencing_the_scientist_tyrone_hayes_on

Silencing the Scientist: Tyrone Hayes on Being Targeted by Herbicide Firm Syngenta
Friday, February 21, 2014
with Amy Goodman & Juan González

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TYRONE HAYES: Well, initially they seemed sort of supportive. You know, we designed more studies. We designed more analysis. And they encouraged me to do more analysis. But as the further analysis just supported the original finding, they became less interested in moving forward very quickly, and eventually they moved to asking me to manipulate data or to misrepresent data, and ultimately they told me I could not publish or could not talk about the data outside of their closed panel.

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Before we published the findings and before the EPA became involved, the company tried to purchase the data. They tried to give me a new contract so that they would then control the data and the experiments. They actually tried to get me to come and visit the company to get control of those data. And when I refused, I invited them to the university, I offered to share data, but they wanted to purchase the data.

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And then that escalated to the company actually—Tim Pastoor, in particular, and others from the company—coming to presentations that—or lectures that I was giving, to make handouts or to stand up and refute the data, and eventually even led to things like threats of violence. Tim Pastoor, for example, before I would give a talk, would literally threaten, whisper in my ear that he could have me lynched, or he would—quote, said he would "send some of his good ol’ boys to show me what it’s like to be gay," or at one point he threatened my wife and my daughter with sexual violence. He would whisper things like, "Your wife’s at home alone right now. How do you know I haven’t sent somebody there to take care of her? Isn’t your daughter there?" So, eventually, it really slipped into some, you know, pretty scary tactics.

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Well, I originally—I had some suspicion that they had hacked into my email. And originally found out—there was a professor at Minnesota, and I was going there to give a big lecture, and this professor in the School of Public Health, Deb Dubenofsky, said that she happened to be standing in line at the airport, flying back to Minnesota, and just by coincidence she was standing behind somebody who was having a conversation on his cellphone and who identified himself as an employee of Syngenta, and he made the statement, "We have access to his email. We know where he is at all times." So it wasn’t just paranoia on my part. I had direct evidence that they had access to my email.

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One recent study has shown that male babies that are exposed in utero to atrazine, their genitals don’t develop properly. Their penis doesn’t develop properly, or they get microphallus. There are studies showing that sperm count goes down when you’re exposed to atrazine. And this is not just laboratory animals or animals in the wild; this is also humans. We use the same hormones that animals do for our reproduction. And it’s a big threat to environmental health and public health.

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See the following for info on the company, including lobbying activities and political contributions. They give about twice as much to Republican candidates as to Democrats.

http://www.sourcewatch.org/index.php/Syngenta

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Former Senator Robert Dole was a lobbyist for Syngenta in 2004.[9]

The company spent over $610,000 and Syngenta Crop Protection, Inc. spent over $390,000 in direct lobbying costs focusing on the federal pesticide laws, biotechnology and EPA’s review of the company’s Atrazine product.[10] In the first 3 months of 2012, the Syngenta Crop Protection has already spent $270,000 on the same issues.[11]

6 of the corporation's 10 lobbyists are revolving door, and have worked for government at some point, including James Richards and Thomas Hunt Shipman who worked for the Dept of Agriculture.

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Syngenta's CEO and Executive Director, Michael Mack, was paid a total compensation in 2010 of $5.45 million. That figure included $1.25 million in salary, a bonus of $206,555, $2.56 million in stock awards, $127,295 in various other awards, and about $380,000 in pension and "deferred compensation earnings."[32] [33]

The Chairman of Syngenta's Board, John Martin Taylor, earned a total compensation package in 2010 of just over $2.46 million, of which $1.85 million was in cash, $382,616 was in stock and $222,880 was in "other compensation."[34]

Jurg Witmer, Syngenta's Vice Chairman of the Board, in 2010 earned a total compensation package of $364,765, of which $342,857 was in cash and $21,908 was in "other compensation.

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