Thursday, March 31, 2016

Patty Duke’s Death Announcement Is A Milestone For Sepsis Awareness

Anna Almendrala
March 30, 2016

Oscar-winning actress Patty Duke, star of “The Patty Duke Show” and the Broadway play and film “The Miracle Worker,” died of sepsis from a ruptured intestine on Tuesday.

Simple though it may seem, her death announcement is a major milestone for the sepsis awareness movement, said Thomas Heymann, executive director of the Sepsis Alliance. The more people are aware of this condition, Heymann said, the stronger their likelihood of saving their own lives or the lives of their loved ones.

“The fact that they said Patty Duke’s cause of death was sepsis is relatively new,” Heymann said. “It very often would have been left as a complication of surgery or an infection, but it’s not a complication — it’s sepsis.”

Sepsis, a reaction to infection that leads to systemic organ failure, kills more than 258,000 Americans every year, according to the U.S. Centers for Disease Control and Prevention, making it the ninth-leading cause of disease-related deaths in the country. While most people can fully recover from sepsis, some survivors are left with permanent organ damage or missing limbs due to amputation.


People who have sepsis experience organ dysfunction caused by their body’s overreaction to an initial infection, whether viral, bacterial or fungal. This overreaction is overwhelming for the body, and can lead to death. It’s most common in people with compromised immune systems, like the very young, the very old and those with chronic diseases like AIDS, cancer, or diabetes. But people can also develop sepsis from a simple scrape, wound or burn that was not properly cleaned.

Sepsis is also on the rise: It was the primary or secondary cause of 1.6 million hospitalizations in 2009, more than double the sepsis-related hospitalizations in 1993, according to a report from the Agency for Healthcare Research and Quality. And it was the single most expensive reason for hospitalizations in 2009, adding up to nearly $15.4 billion in hospital costs.


To avoid deaths by sepsis, Coopersmith has two basic rules for physicians: If a person has an infection, check for organ dysfunction. And if they have organ dysfunction, check for sepsis.

Context also counts for a lot when spotting the signs of sepsis. In addition to symptoms such as high fever, elevated heart rate, or abnormal white blood cell count, a medical history of pneumonia, infection, wounds or urinary tract infections could provide important clues for health care providers, notes a sepsis review published in the journal Nursing Practice.

Other clues, like a patient’s cancer and chemotherapy history — known factors that can suppress the immune system — are stronger clues that an infection could actually be sepsis, notes ABC News.


The signs of sepsis can be broken down in a simple acronym, notes the CDC.

S - Shivering, fever, or feeling very cold
E - Extreme pain or general discomfort, as in “worst ever”
P - Pale or discolored skin
S - Sleepy, difficult to wake up or confused
I - “I feel like I might die”
S - Shortness of breath

Once spotted, doctors treat sepsis by addressing the initial infection, supporting the body’s organs and preventing drops in blood pressure and oxygen levels. But time is of the essence when it comes to sepsis treatment. A 2006 study analyzing over 2,000 septic patients found that over six hours, each hour of a delay in treatment was linked to a 7.6 percent decrease in survival, but treatment within the first hour of a documented drop in blood pressure, a tell-tale sign of sepsis, was linked to an 80 percent survival rate.

Because of this, if you suspect you have sepsis — perhaps after a surgery, or because of a prior infection or wound that isn’t healing well — it’s important to actually say the word “sepsis” to your doctors, the CDC says. They advise patients to say, “I am concerned about sepsis,” in order to get the most timely treatment possible for a potential infection complication. Your life could depend on it, says Coopersmith.

“If you get sepsis, you have a higher chance of dying than if you have a heart attack, stroke or trauma,” Coopersmith said. “There is no question that increasing awareness of sepsis would save lives.”

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