https://www.eurekalert.org/pub_releases/2020-10/ohs-erc102020.php
News Release 20-Oct-2020
Oregon Health & Science University
A review of dozens of studies by researchers at Oregon Health & Science University and Oregon State University suggests that people may shed virus for prolonged periods, but those with mild or no symptoms may be infectious for no more than about 10 days. People who are severely ill from COVID-19 may be infectious for as long as 20 days.
That's in line with guidance provided by the U.S. Centers for Disease Control and Prevention, confirming recommendations for the length of time people should isolate following infection with SARS-CoV-2.
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"Even though people can shed virus for a prolonged period of time, the studies we reviewed indicated that live virus, which may predict infectiousness, was only detected up to nine days in people who had mild symptoms," Sikka said.
The researchers identified 77 studies worldwide, including 59 that had been peer-reviewed, and combed through the results. All studies reported assessments of viral shedding using standard methods to identify the virus by replicating it through a process called polymerase chain reaction, or PCR.
"Although PCR positivity can be prolonged, culture data suggests that virus viability is typically shorter in duration," the authors write.
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