Wednesday, July 03, 2019

Estrogen Promotes Remyelination in Adult Brains of MS Mice, Study Shows


Interesting, since women are much more likely to get MS than are men.

https://multiplesclerosisnewstoday.com/news-posts/2019/04/30/hormones-that-mimic-the-womb-might-help-brain-heal-from-multiple-sclerosis/?utm_content=bufferf3d01&utm_medium=organic+social&utm_source=facebook.com&utm_campaign=buffer&fbclid=IwAR1JQXtzbEq39QZTAUoybHgNurT7_sPQPn4BSCY3NSM_1b2zMvvbkyuoPBA

May 2, 2019 by Patricia Inacio PhD

Giving estrogen to two different adult mouse models of multiple sclerosis (MS), including the experimental autoimmune encephalomyelitis (EAE) model, promoted remyelination, a new study shows.

Exposure to the hormone affected gene activity in oligodendrocytes, tricking them into producing myelin (the fatty substance that protects nerve cells, and that is destroyed in MS). This process appears to mimic the in utero development of the brain, when the fetus is exposed naturally to estrogen in the mother’s blood.

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