Social factors may impact young leukemia patients' survival

http://www.eurekalert.org/pub_releases/2015-09/w-sfm090915.php

Public Release: 14-Sep-2015
Social factors may impact young leukemia patients' survival
Wiley

A new study reveals that insurance status, marital status, and county-level income may affect the chances of survival in young patients with acute myelogenous leukemia (AML). Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings indicate that efforts are needed to address the social factors that impact critical aspects of health in these patients.

AML will affect approximately 20,830 and kill 10,460 Americans in 2015. Tremendous progress has been made in identifying disease characteristics that cause a patient to have a higher or lower chance of cure following intense treatment, which often involves bone marrow transplantation. Now investigators at the University of Alabama at Birmingham have analyzed a database with 5,541 patients younger than 65 years of age to demonstrate that, in addition to age and disease characteristics, other "non-biological" patient characteristics also matter. The study is the largest to date to look at socioeconomic factors in outcomes of younger patients with AML.

Patients who were single or divorced, patients who were uninsured or were Medicaid beneficiaries, and patients who lived in areas with lower income had substantially elevated risks of dying prematurely. "We believe these three factors indicate lack of material and social support preventing young patients from successfully walking the long and difficult road towards a cure," said Uma Borate, MD, lead author of the study, and assistant professor in the UAB Division of Hematology and Oncology.

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