Jet Fuel, Plastics Exposures Cause Disease in Later Generations; Reproductive Diseases, ObesityJet Fuel, Plastics Exposures Cause Disease in Later Generations; Reproductive Diseases, Obesity

http://www.sciencedaily.com/releases/2013/01/130124183630.htm

Jan. 24, 2013 — Washington State University researchers have lengthened their list of environmental toxicants that can negatively affect as many as three generations of an exposed animal's offspring.

Writing in the online journal PLOS ONE, scientists led by molecular biologist Michael Skinner document reproductive disease and obesity in the descendants of rats exposed to the plasticizer bisephenol-A, or BPA, as well DEHP and DBP, plastic compounds known as phthalates.

In a separate article in the journal Reproductive Toxicology, they report the first observation of cross-generation disease from a widely used hydrocarbon mixture the military refers to as JP8.

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The recent PLOS ONE study found "significant increases" in disease and abnormalities in the first and third generations of both male and female descendants of animals exposed to plastics. The first generation, whose mother had been directly exposed during gestation, had increased kidney and prostate diseases. The third generation had pubertal abnormalities, testis disease, ovarian disease and obesity.

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