Increased blood sugar levels may decrease benefits of aerobic exercise

https://www.eurekalert.org/pub_releases/2020-07/jdc-ibs072020.php

News Release 20-Jul-2020
Joslin Diabetes Center


Every doctor recommends regular aerobic exercise, since greater aerobic fitness is important for achieving better overall health. But Joslin Diabetes Center scientists now have discovered that some benefits of aerobic exercise may be dampened by higher-than-normal blood sugar levels, a condition known as hyperglycemia.

These diminished gains are seen in mouse models and humans with chronic hyperglycemia that is in the "prediabetes" range, says Sarah Lessard, PhD, a Joslin assistant investigator in the section of Clinical, Behavioral and Outcomes Research and senior author on a paper in Nature Metabolism that presents the work. The study also showed that this maladaptive trait is independent of obesity and insulin levels in the blood.

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