Friday, July 31, 2020

Your brain parasite isn't making you sick -- here's why

https://www.eurekalert.org/pub_releases/2020-07/uovh-ybp073020.php

News Release 30-Jul-2020
University of Virginia Health System


More than 30 million Americans are infected with a brain parasite spread by cats and contaminated meat, but most will never show symptoms. A new discovery from the University of Virginia School of Medicine explains why, and that finding could have important implications for brain infections, neurodegenerative diseases and autoimmune disorders.

The UVA researchers found that the parasite, Toxoplasma gondii, is kept in check by brain defenders called microglia. These microglia release a unique immune molecule, IL-1α, that recruits immune cells from the blood to control the parasite in the brain, the scientists discovered. This process works so well that very few people develop symptomatic toxoplasmosis, the disease the parasite causes.

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