BPA determined to have adverse effects on couples seeking in vitro fertilization

http://www.eurekalert.org/pub_releases/2016-04/uom-bdt042816.php

Public Release: 28-Apr-2016
BPA determined to have adverse effects on couples seeking in vitro fertilization
University of Missouri-Columbia

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Fred vom Saal, a University of Missouri endocrinologist and researcher, has studied BPA and its effects on the reproductive system for more than 20 years. Now, a new study has corroborated his work showing that BPA causes a linear increase in the death rate of embryos and could be the cause for decreases in the frequency of implantation, pregnancy and live birth rates in couples seeking in vitro fertilization (IVF). Vom Saal, who wrote a review of the study, says that this is more proof that BPA usage should cease.

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BPA is one of the highest volume endocrine disrupting chemicals used in commerce, with current estimates determining that more than 7.7 million tons of the chemical being are produced each year. Additionally, since thousands of dollars can be spent during an IVF cycle and BPA has been proven to alter signaling mechanisms involving estrogen and other hormones required for successful IVF, it is likely that BPA is producing financial and emotional stress on couples seeking the procedure, vom Saal said.

"Previous studies have shown that BPA damages both sperm and eggs; these results have been demonstrated in both animals and humans," vom Saal said. "The findings by Chavarro and colleagues show that the probability of having a surviving embryo goes from more than 50 percent to under 20 percent as levels of BPA increase. Nearly 20 years after my lab and others reported the first adverse reproductive effects in animals, BPA has finally begun to be identified as a reproductive toxicant by authorities. As findings continue to mount and confirm that daily exposure to BPA is a reproductive toxicant, it becomes vital to regulate and control this chemical."