PCBs, other pollutants may play role in pregnancy delay

http://www.eurekalert.org/pub_releases/2012-11/nioc-pop111212.php

Public release date: 14-Nov-2012
Contact: Robert Bock or Marianne Glass Miller
NIH/National Institute of Child Health and Human Development
NIH study finds delays after exposure to pesticides, industrial chemicals

Couples with high levels of PCBs and similar environmental pollutants take longer to achieve pregnancy in comparison to other couples with lower levels of the pollutants, according to a preliminary study by researchers at the National Institutes of Health and other institutions.

PCBs (polychlorinated biphenyls) are chemicals that have been used as coolants and lubricants in electrical equipment. They are part of a category of chemicals known as persistent organochlorine pollutants and include industrial chemicals and chemical byproducts as well as pesticides. In many cases, the compounds are present in soil, water, and in the food chain. The compounds are resistant to decay, and may persist in the environment for decades. Some, known as persistent lipophilic organochlorine pollutants, accumulate in fatty tissues. Another type, called perfluorochemicals, are used in clothing, furniture, adhesives, food packaging, heat-resistant non-stick cooking surfaces, and the insulation of electrical wire.

Exposure to these pollutants is known to have a number of effects on human health, but their effects on human fertility-- and the likelihood of couples achieving pregnancy-- have not been extensively studied.

"Our findings suggest that persistent organochlorine pollutants may play a role in pregnancy delay," said the study's first author, Germain Buck Louis, Ph.D., director of the Division of Epidemiology, Statistics, and Prevention Research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) at NIH.