Tuesday, September 07, 2021

Prior exposure to common cold coronaviruses enhances immune response to SARS-CoV-2


https://www.eurekalert.org/news-releases/927282

 

News Release 2-Sep-2021
Peer-Reviewed Publication
Charité - Universitätsmedizin Berlin

 

Researchers from Charité – Universitätsmedizin Berlin, the Berlin Institute of Health at Charité (BIH) and the Max Planck Institute for Molecular Genetics (MPIMG) have shown that certain immune cells, which are found in people previously exposed to common cold coronaviruses, enhance the body’s immune response to SARS-CoV-2, both during natural infection and following vaccination. The researchers, whose work has been published in Science*, also report that this ‘cross-reactive immunity’ decreases with age. This phenomenon may help to explain why older people are more susceptible to severe disease and why their vaccine-induced immunity is often weaker than that of young people.


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