https://www.eurekalert.org/pub_releases/2020-12/aaon-smm121120.php
News Release 16-Dec-2020
American Academy of Neurology
People with the advanced form of multiple sclerosis (MS) called secondary progressive MS who took the drug siponimod for one to two years had improved cognitive processing speed compared to those who did not take the drug, according to a new study published in the December 16, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Cognitive processing speed is the amount of time it takes someone to take in information, process it and then react to solve a problem or complete a task. It can affect many aspects of a person's daily life including employment, driving skills and social activities.
While most people with MS are initially diagnosed with relapsing-remitting MS, marked by symptom flare-ups followed by periods of remission, most eventually transition to secondary progressive MS, which does not have wide swings in symptoms but instead a slow, steady, worsening of the disease.
"Multiple sclerosis is a neurodegenerative disease, meaning neurons in the brain can break down or die, and this can greatly affect a person's thinking skills," said study author Ralph H. B. Benedict, Ph.D., of the University of Buffalo in New York, and a member of the American Academy of Neurology. "While there are currently no drugs on the market in the United States approved for the treatment of cognitive impairment in MS, our study found that siponimod, which is prescribed to slow the progression of physical disability in MS, may also help improve cognitive processing speed in people with advanced MS."
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