https://www.eurekalert.org/pub_releases/2020-09/tmsh-rvf091020.php
News Release 10-Sep-2020
The Mount Sinai Hospital / Mount Sinai School of Medicine
New York - In a study published in JAMA today, Mount Sinai researchers report findings that shed some light on the disproportionate impact of COVID-19 on Blacks, who have experienced rates of infection and death that are much greater, in some areas twice and three times more, than their proportion of the population. "Our study suggests one factor that may partially contribute to COVID-19 risk among Blacks," says lead author, Supinda Bunyavanich, MD, MPH, Professor of Genetics & Genomic Sciences and Pediatrics, Icahn School of Medicine at Mount Sinai.
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An important point is that gene expression is a dynamic reflection of personal, social, and environmental history, and many complex factors contribute to health disparities."
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"One of the key takeaways of our findings is the critical importance of including diverse participants in clinical trials," says Dr. Bunyavanich. "In clinical trials of TMPRSS2 inhibitors, it's possible that different effects may be seen depending on racial/ethnic background. More broadly, we also need to address the social determinants of health, economic disparities, and differential access to health care that drive racial/ethnic disparities in health."
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