Common drugs tied to increased risk of cognitive decline

https://www.eurekalert.org/pub_releases/2020-09/aaon-cdt083120.php

News Release 2-Sep-2020
American Academy of Neurology

A class of drugs used for many conditions, including allergies, colds, high blood pressure and depression, may be associated with an increased risk of developing mild thinking and memory problems, particularly in people who have genetic risk factors for Alzheimer's disease or markers of this condition, according to a study published in the September 2, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. These types of drugs, called anticholinergic drugs, are used for motion sickness, urinary incontinence, overactive bladder, Parkinson's disease and high blood pressure. There are approximately 100 such drugs in widespread use, with some requiring a prescription and many others that may be purchased over the counter.

The study found that cognitively normal people taking at least one anticholinergic drug were 47% more likely to develop mild cognitive impairment, which can be a precursor to dementia, over the next decade than people who were not taking such drugs. 

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