https://www.eurekalert.org/pub_releases/2020-05/uosa-ecc051320.php
News Release 13-May-2020
University of South Australia•••••
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Using data from over 300,000 participants in the UK Biobank, researchers examined connections between genetically instrumented habitual coffee consumption and a full range of diseases, finding that too much coffee can increase the risk of osteoarthritis, arthropathy (joint disease) and obesity.
In earlier research conducted by Professor Hyppönen and team, six cups of coffee a day were considered the upper limit of safe consumption.
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"Typically, the effects of coffee consumption are investigated using an observational approach, where comparisons are made against non-coffee-drinkers. But this can deliver misleading results.
"In this study, we used a genetic approach - called MR-PheWAS analysis - to establish the true effects of coffee consumption against 1117 clinical conditions.
"Reassuringly, our results suggest that, moderate coffee drinking is mostly safe.
"But it also showed that habitual coffee consumption increased the risks of three diseases: osteoarthritis, arthropathy and obesity, which can cause significant pain and suffering for individuals with these conditions."
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